Cannabidiol (CBD) is a non-intoxicating component of the cannabis plant and is one of the most studied compounds in the world. It has been found to have a wide range of potential therapeutic benefits, ranging from anxiety relief to reducing inflammation. Over the last few years, there has been an increase in research into CBD and its effects on the human brain. It is thought that CBD interacts with the body’s endocannabinoid system (ECS), which is responsible for maintaining homeostasis in the body. The ECS is composed of receptors known as CB1 and CB2, which are found in different parts of the body including the brain. These receptors interact with chemicals called cannabinoids, which can either activate or inhibit them depending on their chemical makeup. When CBD enters the body, it binds to these receptors and activates them. This causes various reactions throughout the body, including changes in neurotransmitter levels. Neurotransmitters are chemicals that transmit signals between neurons and play an important role in regulating behavior, mood, and cognitive function. By interacting with these receptors, CBD has been found to influence serotonin levels, resulting in increased feelings of relaxation and reduced anxiety. It has also been found to reduce inflammation in the brain by altering levels of cytokines—proteins released by cells that play an important role in inflammation. In addition to its influence on neurotransmitters, CBD also affects other areas of the brain. It has been found to stimulate neurogenesis—the process by which new neurons are formed—in certain regions of the brain such as the hippocampus, which plays a key role in learning and memory formation. Additionally, CBD may also help protect against damage caused by oxidative stress and reduce symptoms associated with certain neurological conditions such as Alzheimer’s disease and Parkinson’s disease. Overall, CBD has been found to have a wide range of effects on the human brain due to its interaction with CB1 and CB2 receptors located within it. From influencing neurotransmitter levels to stimulating neurogenesis, it appears that CBD could be an effective therapeutic option for those looking for relief from various conditions related to mental health or neurological disorders.